The protein fingerprint detection kit that has been monopolized by foreign products has been successfully developed and put on the market by Zhejiang Huzhou Serdi Biomedical Technology Co., Ltd.
According to reports, the protein fingerprint spectrometer used with the kit can be widely used in the analysis and testing fields such as medicine, food, environment, drug development and national security, but it has long relied on imports. It is estimated that the price is only 1/3 of similar foreign products.
How amazing is protein fingerprinting technology? During the interview, Dr. Xu Yang, chairman of Huzhou Serdi Biomedical Technology Co., Ltd. told reporters that with the completion of human genome sequencing, humans have the key to decoding the essence of life. However, there are only about 30,000 human genes, which is much less than the expected number, which does not match human's ever-changing individual differences and disease performance. In fact, thousands of scenes of life are expressed through the gene product protein, and the number of human protein is about 100,000. Therefore, fully mining and using the extremely rich information in proteins is of great significance for understanding the physiological and pathological activities of the human body and detecting the occurrence and development of diseases.
According to the report of the authoritative American journal "Tumor Research", protein fingerprinting technology can detect the protein fingerprint of prostate cancer 5 years ago. Because tumor markers are sensitive, when the number of tumor cells reaches tens of millions, biochemical changes such as proteins, enzymes, or oncogenes can be detected in serum and urine.
What is the concept of protein fingerprint? Dr. Xu Yang explained that just as everyone's fingerprint is different from others, the specific protein expressions of each disease are also different. Calling the fingerprint is a metaphor. Protein fingerprinting technology is composed of protein chip and analytical instrument-surface enhanced laser analysis ionization time-of-flight mass spectrometry. It can record the changes of protein composition in the patient's serum, draw a protein fingerprint mass spectrogram, and display various proteins in the sample. Molecular weight, content and other information. By comparing this spectrum with the spectrum of normal people, patients with certain diseases, or the spectrum in the gene library, you can finally discover and capture new specific related proteins and their characteristics. The entire measurement is usually completed in tens of minutes. carry out.
The protein fingerprint of a person is in a dynamic and constantly changing process. Through this technology, people may have their own life CD in the future, record the protein fingerprint at different stages of their life, understand and observe their physiology from the molecular level Change, or as a reference for comparison before and after treatment. This technology is currently mainly used in tumor auxiliary diagnosis, dynamic observation and curative effect evaluation in major domestic hospitals. The one-time test of five hundred yuan is quite popular in the market.
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